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Clinical Trials/NCT04141267
NCT04141267
Completed
Not Applicable

Feasibility of Isoflurane Sedation Using an Anesthetic-conserving Device in Prehospital Emergency Medicine: A Retrospective Study

University Hospital, Brest1 site in 1 country10 target enrollmentMay 3, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endotracheal Intubation
Sponsor
University Hospital, Brest
Enrollment
10
Locations
1
Primary Endpoint
depth of sedation
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine. Inhaled sedation is possible with the Anesthetic-conserving device with a standard respirator.

The pharmacodynamics and pharmacokinetics of halogenated agents allow deep sedation quickly after absorption.

The feasibility of inhaled sedation has never been studied in hospital.

Detailed Description

Retrospecive clinical monocentric study with sedated ventilated patients with isoflurane with the AnaConda® system out of hospital.

Registry
clinicaltrials.gov
Start Date
May 3, 2019
End Date
June 3, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient sedated by isoflurane with Anesthetic-conserving device in pre-hospital
  • Major patient
  • not opposed to participating

Exclusion Criteria

  • Adults Under legal protection
  • patient refusal to participate in study

Outcomes

Primary Outcomes

depth of sedation

Time Frame: up to 1 day

depth of sedation (measured by the Ramsay Score) 10 minutes from start of the sedation and at stop of pre hospital sedation. The Ramsay score ranges level of sedation from 1(patient anxious ,agitated,restless) to 6 (patient exhibits no response).

Secondary Outcomes

  • hemodynamic tolerance of patients during isoflurane sedation(up to 1day)

Study Sites (1)

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