MedPath

Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort)

Not Applicable
Completed
Conditions
Glaucoma
AMD
Interventions
Procedure: Optical Coherence Tomography
Registration Number
NCT01766596
Lead Sponsor
Centre Hospitalier Universitaire Dijon
Brief Summary

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.

The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1153
Inclusion Criteria
  • Persons who have given their written consent
  • Persons who are taking part in the Dijon 3C study
Exclusion Criteria
  • Persons who are not registered with social security agency
  • Persons who are unable to sit upright during a consultation

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
3C cohortOptical Coherence Tomography-
Primary Outcome Measures
NameTimeMethod
Measure the mean thickness of postganglionic fibersT=7 years of the 3C cohort

Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CHU Dijon

🇫🇷

Dijon, France

© Copyright 2025. All Rights Reserved by MedPath