A Crossover Study to Compare Lung Flute Method to Hypertonic Saline Inhalation Method in Induced Sputum in Healthy Japanese Adults Smorkers or Non Smorkers
- Conditions
- Healthy Adults
- Registration Number
- JPRN-UMIN000023505
- Lead Sponsor
- Kitasato University Hospital Clinical trial Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 80
Not provided
1) Any subject with malignant neoplasm, of with a previous history of malignant neoplasm 2) Any subject being contracted by severe disease (circulatory disease, liver disease, kidney disease, blood disease, respiratory disease, chronic respiratory disease, asthma, bronchitis, endocrine metabolic disease or electrolyte imbalance) or having been contracted thereby in the past. 3) Any subject known to abuse drugs or who tests positive for a drug in urine screening tests. 4) Any subject with a positive serological response for syphilis, HIV antigen or antibody, HBs antigen, or HCV antibody. 5) Use of any medicine within 2 weeks before Screening day, need to use of any medicine during this study. 6) Those who used "stop smoking aid" within four weeks before screening or until end of second survey. 7) Participation in any other clinical trial within the past 16 weeks. 8) Persons who have donated more than 200 ml of blood in the past 4 weeks or more than 400 ml of blood in the past 12 weeks (more than 200 ml of blood in the past 4 weeks or more than 400 ml of blood in the past 16 weeks in female). 9) Women who are pregnant, maybe pregnant or lactation. 10) Women who can't use birth control during the period from screening to second survey. 11) Women who are lactation. 12) Any condition that, in the opinion of the investigator, would make the patient unsuitable for inclusion in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Induced Sputum rate
- Secondary Outcome Measures
Name Time Method Safety, Evaluation of Induced Sputum, Background