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临床试验/NCT02129907
NCT02129907已完成不适用

The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.

HaEmek Medical Center, Israel1 个研究点 分布在 1 个国家目标入组 82 人开始时间: 2013年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
82
试验地点
1
主要终点
thrombin generation levels

研究概览

简要总结

In total 50 subjects with iron deficiency anemia treated with intravenous iron are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant before iron treatment. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). patient will go face to face interview and will be asked to answer structured questionnaire which will include information on demographics, clinical data ( fever, allergies , etc.) and comorbidities

Two weeks after completing intravenous iron administration additional blood samples will be taken: thrombin generation will be measured

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age >18 years
  • Iron deficiency anemia that did not response to oral iron treatment and is planned to receive iron supplement intravenously.
  • Signing the informed consent
  • exclusion criteria:
  • chronic inflammatory disease
  • renal failure
  • Malignancy
  • Infectious disease
  • Other reason for anemia except iron deficiency anemia.
  • Pregnant women
  • Use of anti aggregating agents or anticoagulants

排除标准

  • 未提供

结局指标

主要结局

thrombin generation levels

时间窗: 10 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elias mazen

prof mazen elias

HaEmek Medical Center, Israel

研究点 (1)

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