Comparision of epidural analgesia with transversus abdominis plane block in renal transplant recipients

Completed

• Conditions: End stage renal disease,

• Registration Number: CTRI/2016/12/007577
• Lead Sponsor: PGIMER

Brief Summary

Although continuous TAPblock has been compared with epidural analgesia in laparoscopic surgeries, tothe best of our knowledge a study directly comparing the technique withepidural analgesia has not been performed in renal transplantrecipients. The existing study was designed to directly **comparecontinuous TAP block with continuous patient controlled epidural blockade** todetermine whether TAP block can provide a useful alternative to epiduralanalgesia in this subset of patients.

The studyhypothesizes that transversus abdominis plane block is a non inferior analgesictechnique to continuous epidural analgesia in renal transplant recipients.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-08
• Study Completion: 2015-11-30
• Last Update Posted: 2019-11-19

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

Patients with end stage renal disease scheduled to undergo live donor renal transplant.

Exclusion Criteria

• 1.Refusal to give consent.
• 2.Derangements of coagulation profile contraindicating the use of epidural anaesthesia (INR of ≥1.3 will be considered a cut-off for the study).
• 3.Addiction to opioids, or alcohol, or history of any other substance abuse.
• 4.Allergy to local anaesthetic drugs.
• 5.Extension of surgical incision lateral to anterior axillary line or above T8 dermatome.
• 6.Inability to communicate (e.g. known psychiatric disorders).
• 7.Accidental complications such as dural puncture or peritoneal breach.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Numerical Pain rating scale score postoperatively	Numerical Pain rating scale score at 0, 1, 2, 4, 6, 12, 24 hours postoperatively

Secondary Outcome Measures

Name	Time	Method
Requirement of postoperative opioid (fentanyl) in the first 24 hours postoperatively	24 hours postoperatively
Patient satisfaction with the analgesia regimen.	24 hours postoperatively

Trial Locations

Locations (1)

Postgraduate Institute of Medical Education and Research; 🇮🇳 Chandigarh, CHANDIGARH, India

Postgraduate Institute of Medical Education and Research

🇮🇳Chandigarh, CHANDIGARH, India

Dr HEMANT OJHA

Principal investigator

8195921555

hemantojha@hotmail.com