The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients
- Conditions
- Chronic Periodontitis, Generalized
- Interventions
- Combination Product: amoxicillin 500mg and metronidazole 400mg
- Registration Number
- NCT03783845
- Lead Sponsor
- Taibah University
- Brief Summary
Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?
- Detailed Description
The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes.
Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 44
Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis
Pregnancy
- Alcoholism and smoking
- Presence of any systemic disorders other than hypertension and diabetes
- Diabetic major complications
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description test group amoxicillin 500mg and metronidazole 400mg Metronidazole 400mg,three times daily for two weeks Amoxicillin 500mg,three times daily for two weeks.
- Primary Outcome Measures
Name Time Method glycosylated haemoglobin (HbA1c) 3 months Blood was taken from a peripheral vein to monitor HbA1c using high-performance liquid chromatography
- Secondary Outcome Measures
Name Time Method