Effectiveness of intrauterine insemination with ovarian hyperstimulation in couples with an unexplained moderately reduced fertility.
Completed
- Conditions
- nexplained subfertility.
- Registration Number
- NL-OMON25051
- Lead Sponsor
- OFO-projectt.a.v. B.W. MolAcademic Medical CenterCenter of Reporductive medicine, H4-213Postbus 226601100 DD AmsterdamPhone: 0031205663857Fax: 0031206963489e-mail: ofoproject@amc.uva.nl or b.mol1@chello.nl
- Brief Summary
ancet. 2006 Jul 15;368(9531):216-21. <br><br> Ned Tijdschr Geneeskd. 2008 Jul 5;152(27):1525-31.<br><br> Partly presented in a poster presentation at the 21st Annual Meeting of the European Society of Human Reproduction and Embryology, Copenhagen, 2005.<br> <br><br> Will be presented in an oral presentation at the Gynaecongres of november 2005.<br>
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
All subfertile couples in whom no reason is found during the basic fertility work-up for their subfertility and in whom their spontaneous pregnancy chance in the next year, calculated by the results of the basic fertility work-up, is between 30% and 40%.
Exclusion Criteria
All couples in whom a reason is found for their subfertility or who are having an other prognosis calculated.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint was ongoing pregnancy within six months. Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks.
- Secondary Outcome Measures
Name Time Method Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies.