The effectiveness of intrauterine insemination in subfertile couples with an isolated cervical factor: a randomised controlled trial.
Completed
- Conditions
- subfertility
- Registration Number
- NL-OMON26297
- Lead Sponsor
- OFO-projectt.a.v. B.W. MolAcademic Medical CenterCenter of Reporductive medicine, H4-213Postbus 226601100 DD AmsterdamPhone: 0031205663857Fax: 0031206963489e-mail: ofoproject@amc.uva.nl or b.mol1@chello.nl
- Brief Summary
Fertil Steril. 2007 Dec;88(6):1692-6. Epub 2007 May 7. <br> <br><br> Partly presented in an oral presentation at the Conjoint Annual Meeting of the American Societty for Reproductive Medicine and the Canadian Fertility and Andrology Society, ASRM/CFAS 2005, Montreal, Quebec, Canada.<br>
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Couples with a cervical factor and otherwise no factors that reduced their fertility, i.e. a prognosis for a treatment independent ongoing pregnancy in the next year higher than 30%. A cervical factor was diagnosed by a well-timed, non-progressive post-coital test (PCT) with normal semen parameters.
Exclusion Criteria
All other subfertile couples.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint was ongoing pregnancy within six months. Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks.
- Secondary Outcome Measures
Name Time Method Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies.