Stellate Ganglion Block on Tourniquet Response
- Conditions
- Stellate Ganglion Block
- Interventions
- Procedure: Stellate ganglion blockProcedure: control group
- Registration Number
- NCT03181672
- Brief Summary
To investigate the influence of stellate ganglion block on tourniquet response during surgery in patients undergoing elective lower limb Department of orthopedics.
- Detailed Description
Select elective general anesthesia in 100 cases of lower extremity Department of orthopedics surgery patients were randomly divided into SGB group and control group, SGB group received anesthesia before the right stellate ganglion block intervention, the control group underwent right deltoid muscle injection, changes in hemodynamics in two groups were recorded in heart rate, blood pressure, and before anesthesia, after intubation 3min 1H, a tourniquet, tourniquet release before and after tourniquet release 3min, 30min, changes in blood physiological analysis. The effect of stellate ganglion block on tourniquet response during perioperative period was observed.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- American Society of anesthesiologists Grade 1-3 Patients
- undergoing lower limb surgery under general anesthesia
- should be treated with tourniquet
- Tourniquet application time is less than 1h, greater than 1.5h
- Abnormal coagulation function
- perioperative application of hormone
- lidocaine allergy
- can not cope with nerve block
- nerve block failure
- minimally invasive surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Stellate ganglion block Stellate ganglion block Stellate ganglion block control group control group Deltoid muscle injection
- Primary Outcome Measures
Name Time Method heart rate 2 hours in perioperative period bpm
ET-1 One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA ng/L
SOD One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA μg/L
IL-6 One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA pg/ml
cTn-T One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA μg/L
blood pressure 2 hours in perioperative period mmHg
Lac One minute after the radial artery puncture, the tourniquet was applied for 1 hours and the tourniquet was released 3 minutes after the tourniquet release 30 minutes blood gas analysis mmol/L
norepinephrine One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA nmol/L
cortisol One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA ng/ml
postoperative pain hour 1、hour 6、hour 24、hour 48 after operation VAS score
MDA One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet ELISA nmol/ml
- Secondary Outcome Measures
Name Time Method Complication of puncture 2 hours in perioperative period bleeding、nerve injury、
Trial Locations
- Locations (1)
The Affiliated Hospital of Xuzhou Medical University
🇨🇳Xuzhou, Jiangsu, China