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Clinical Trials/NCT01107223
NCT01107223
Unknown
N/A

Long Term Effect of General Practitioner Education on Antibiotic Prescribing: a Large Scale Randomized Study

Henri Mondor University Hospital1 site in 1 country170 target enrollmentSeptember 2004

Overview

Phase
N/A
Intervention
Not specified
Conditions
Respiratory Tract Infections
Sponsor
Henri Mondor University Hospital
Enrollment
170
Locations
1
Primary Endpoint
Change in the percentage of prescriptions containing an antibiotic between control and intervention groups (seminar on the treatment of respiratory tract infections).
Last Updated
16 years ago

Overview

Brief Summary

Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance. The aim of this trial was to assess the long-term effect of a continuous education program on general practitioners antibiotic prescribing behaviour. 170 physicians were included in this study. Physicians randomized in the education group attended a two days seminar focused on evidence-based guidelines on antibiotic use in respiratory tract infections. The intervention was limited at physicians level and did not target the patients.

Registry
clinicaltrials.gov
Start Date
September 2004
End Date
April 2010
Last Updated
16 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Henri Mondor University Hospital

Eligibility Criteria

Inclusion Criteria

  • General practitioners practicing in three departments of the Parisian area in France
  • General practitioners attending a two days didactic educational meeting on evidence-based guidelines for diagnosis and treatment of acute respiratory tract infection.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in the percentage of prescriptions containing an antibiotic between control and intervention groups (seminar on the treatment of respiratory tract infections).

Time Frame: Effect of the intervention 4 to 6 months after the educational training.

All prescriptions written by all general practitioners enrolled in the study were extracted each year from the French National Health System database. All data were compared to 2004 (baseline). Education group GPs attended a two-day seminar presenting evidence-based guidelines on antibiotic prescription in respiratory tract infections. The change (compared to baseline) in the percentage of prescriptions containing an antibiotic (antibiotic prescription rates) was compared between control and intervention groups.

Change in the cost of antibiotic prescription between control and intervention groups (seminar on the treatment of respiratory tract infections).

Time Frame: Effect of the intervention 4 to 6 months after the educational training.

All prescriptions written by all general practitioners enrolled in the study were extracted each year from the French National Health System database. All data were compared to 2004 (baseline). Education group GPs attended a two-day seminar presenting evidence-based guidelines on antibiotic prescription in respiratory tract infections. The change (compared to baseline) in the cost of antibiotic prescription was compared between control and intervention groups.

Secondary Outcomes

  • Long term antibiotic prescription rates(Effect of the intervention 28 to 30 months after the educational training.)
  • Long term antibiotic cost.(Effect of the intervention 28 to 30 months after the educational training.)
  • Symptomatic drug prescription rates(Effect of the intervention 28 to 30 months after the educational training.)
  • Symptomatic drug cost.(Effect of the intervention 28 to 30 months after the educational training.)
  • Effect of patient age.(Effect of the intervention 28 to 30 months after the educational training.)
  • Effect of a seminar on problem-solving strategy on prescriptions.(Effect of the intervention 28 to 30 months after the educational training.)

Study Sites (1)

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