跳至主要内容
临床试验/NCT06592469
NCT06592469尚未招募不适用

The Outcome of Ureteroscopy in Fresh Versus Recurrent Cases of Stone Ureter (Post-ESWL, Endoscopy, or Open Surgery)

Assiut University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1
主要终点
Stone free rate of Urereroscopy in fresh versus recurrent cases of stone ureter

研究概览

简要总结

Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter

详细描述

Urolithiasis is a common cause of both urology outpatient clinic and emergency room encounters. Approximately 75-90% of ureteral stones pass spontaneously. from this point of view other managements of ureteric stones either ESWL, ureteroscopy or open surgery according to location, site, size, and density. Ureteroscopy is commonly used to diagnose and treat kidney and ureteral stones, ureteral strictures, and urothelial cancers. Semirigid URS is the gold standard of treatment for ureteral stones. High success rates and low morbidity have been reported in semirigid URS. but complications still occur in some cases. The possibility to predict their occurrence should influence patient advisement and better case selection. there are many predictors of successful URS as age, gender, previous ESWL, and stone character. In addition, the impacted stone is a risk factor, and it is described in the literature as ureteral wall thickness, higher grades of hydronephrosis, ureteral stricture, polyp, inflammatory reaction, and difficulty to introduce the guide wire. the literature is very poor in illustrating the previous procedures as a predictor of successful URS only seen in very few original articles as second-time URS after any procedure decreases the rate of success, so it is a point of research that Amr Moustafa aims to clarify. Amr Moustafa will conduct a prospective study to evaluate the outcomes of URS for stones in the fresh and recurrent cases.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • • all cases with middle and lower ureteric stone candidate for endoscopy.
  • Stone 15mm or less.

排除标准

  • • Patients with a ureteral stent.
  • Patient refusing participation.
  • Pregnant woman.
  • Active urinary tract infection.
  • Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.

结局指标

主要结局

Stone free rate of Urereroscopy in fresh versus recurrent cases of stone ureter

时间窗: 1 day post operative by MSCTKUB or Plain KUB to determine residual stones post operative

• Stone free rate with a mean operative time of 1 hr by MSCTKUB or Plain KUB to determine residual stones post operative

次要结局

  • • Rate of intraoperative findings in each group.(Intraoperative)
  • • The rate of complication in each group(Intraoperative by ureteroscope and one day post operative by MSCT)
  • • The rate of stone impaction in each group(Intraoperative by ureteroscope)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amr Moustafa Hussein Soliman

Resident doctor

Assiut University

研究点 (1)

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