Impact of Nordic Walking intervention on the characterization of exosomes in frail elderly
Not Applicable
- Conditions
- Health Condition 1: R54- Age-related physical debility
- Registration Number
- CTRI/2023/06/053418
- Lead Sponsor
- Indian Council of Medical Research (ICMR)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age >= 65 years
2.Consent by Patient or Legal Representative
3.Frailty syndrome (>=1 positive out of 5
standardized parameters according to the Physical
Frailty Phenotype according to Fried et. al.)
Exclusion Criteria
•Severe cardiac or pulmonary disease (NYHA IV, Gold IV)
•Intracranial interventions
•Moribund patients (palliative situation)
•Not enough language skills
•Participation in another interventional rehabilitation study or other interventional clinical trial that has not been approved by the study management committee (Exception: Participation in adjuvant intervention study)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Present study will provide the insight into expression profiling of cytokines & chemokines in frail elderly patients. And the impact of Nordic walking will help analyze the alteration in expression profile of the inflammatory proteins. Additionally it will also help in understanding the molecular alterations via plasma derived exosomes. Furthermore study would also help in identifying and explore the potential of the altered molecules as biomarker in frail elderly group.Timepoint: at baseline & at three months
- Secondary Outcome Measures
Name Time Method not applicableTimepoint: not applicable