EFFECT OF HIGH VERSUS LOW-VOLUME HIGH INTENSITY INTERVAL TRAINING ON GLYCEMIC AND LIPIDS CONTROL IN TYPE 2 DIABETES
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diabetes Mellitus
- Sponsor
- Cairo University
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- fasting & 2-h post prandial blood glucose
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Recently, HIIT has been recommended by the American diabetes association for type 2 diabetes. The high-volume HIIT has been studied extensively in patients with type 2 diabetes, however, little is known about the effectiveness of low-volume HIIT regarding target glycemic or lipid control in these patients. Therefore, the purpose of this study is to compare between two subtypes of HIIT (i.e. the low-volume HIIT versus the high-volume HIIT) with respect to exercise-induced changes in blood glucose, lipid profile and anthropometry in patients with type 2 diabetes mellitus. Statement of the Problem Is there any difference between the effect of high-volume and the low-volume high intensity interval training on glycemic and lipids control in type 2 diabetes?
Purpose of the study:
To assess the effect of the high-volume versus the low-volume high intensity interval training on glycemic and blood lipids control in type 2 diabetes.
Null Hypothesis:
There will be no difference between the effect of the high-volume versus the low-volume high intensity interval training on glycemic and blood lipids control in type 2 diabetes.
Investigators
Asmaa Mohamed Mahmoud Mohamed
physiotherapist holds a master's degree in Physical therapy for Cardiovascular, Respiratory disorders and geriatrics, Faculty of physical therapy, Cairo university.
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Type II diabetes mellitus diagnosed by a physician as having HbA 1c of \> 6.5%.
- •An established diagnosis of T2DM for at least 1year and less than 5 years.
- •Women patients.
- •Age between 35 to 45 years old.
- •Systolic Blood pressure less than or equal 130 mmHg.
- •Obese patients (BMI is between 30 and 39.9 kg/m 2 )
- •Patients with HbA 1c of 7-9%.
- •A self-reported sedentary lifestyle.
- •Patients receiving oral hypoglycemic medications described by the physician
- •Patients with hyperlipidemia.
Exclusion Criteria
- •Patients with Cardiac diseases.
- •Patients with glaucoma.
- •Patients with diabetic complications (Diabetic foot, retinopathy, nephropathy, and diabetic peripheral neuropathy).
- •Musculoskeletal or neurological limitations to physical exercise.
- •Patients under insulin therapy
- •Patients with poorly controlled DM (HbA1c \> 9%)
- •Bronchial asthma and chronic obstructive pulmonary disease.
- •Morbidly obese BMI ≥ 40 kg/m 2
- •Systolic Blood pressure more than 130 mmHg.
- •Anemia ( hemoglobin \< 12 g/dL)
Outcomes
Primary Outcomes
fasting & 2-h post prandial blood glucose
Time Frame: 12 weeks
change in fasting \& 2-h post prandial blood glucose
body mass index
Time Frame: 12 weeks
change in body mass index
waist circumference
Time Frame: 12 weeks
change in waist circumference
waist/hip ratio
Time Frame: 12 weeks
change in waist/hip ratio
Systolic and diastolic blood pressure
Time Frame: 12 weeks
change in Systolic and diastolic blood pressure
HbA1c
Time Frame: 12 weeks
change in HbA1c
fasting lipid profile
Time Frame: 12 weeks
change in fasting lipid profile