Can an acute dosage of Bacopa Monniera (brahmi) improve cognition, cardiovascular function and stress in a healthy older populatio

Phase 3

Recruiting

• Conditions: Cognitive function in healthy older individuals; Cardiovascular function in healthy older individuals; Stress; Alternative and Complementary Medicine - Herbal remedies; Cardiovascular - Normal development and function of the cardiovascular system; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12609000717257
• Lead Sponsor: Swinburne University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-08-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Free from psychiatric disorders
- No neurological diseases
- Not suffering from endocrine, gastrointestinal or bleeding disorders
- No history of chronic illness/infection
- Not currently pregnant or lactating
- Must not be taking anticoagulants, antidepressants, antipsychotics, anxiolytics, acetylcholine esterase (AChE) inhibitors, anti-Parkinson’s medication, illicit drugs or any cognitive enhancing drugs
- Must have corrected to normal vision
- Non smoker

Exclusion Criteria

- Smokers
- Psychiatric disorder
- Neurological diseases
- Suffering from endocrine, gastrointestinal or bleeding disorders
- A history of chronic illness/infection
- Pregnant or lactating
- Taking anticoagulants, antidepressants, antipsychotics, anxiolytics, AChE inhibitors, anti-Parkinson’s medication, illicit drugs or any cognitive enhancing drugs
- Vision that is not normal or corrected to normal

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive Function using Cognitive Drug Research (CDR) battery, Swinburne University Computerised Cognitive aging Battery (SUCCAB) battery[Baseline and 2 hours post dose];Cardiovascular function using transcranial doppler ultrasound and arterial stiffness measure (using sphygmocor system)[Baseline and 2 hrs post dose]

Secondary Outcome Measures

Name	Time	Method
Stress/mood using multitasking battery to induce stress and mood questionnaires before and after stress task[Baseline and 2 hrs post dose]