Can an acute dosage of Bacopa Monniera (brahmi) improve cognition, cardiovascular function and stress in an elderly populatio

Phase 3

Completed

• Conditions: Cognitive function in healthy elderly individuals; Mental Health - Studies of normal psychology, cognitive function and behaviour; Cardiovascular function in healthy elderly individuals; Stress; Alternative and Complementary Medicine - Herbal remedies; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12611001230943
• Lead Sponsor: Swinburne University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1.) Healthy non-smoking males and females aged 65 and over
2.) Free from and no history of psychiatric disorders
3.) No neurological diseases or history of neurological diseases
4.) Not suffering from endocrine, gastrointestinal or bleeding disorders
5.) No history of chronic illness/infection
6.) Not currently pregnant or lactating
7.) Must not be taking any medications or herbal extracts
8.) Must have corrected to normal vision

Exclusion Criteria

1.) smoker
2.) history of psychiatric disorders
3.) neurological diseases or history of neurological diseases
4.) endocrine, gastrointestinal or bleeding disorders
5.) history of chronic illness/infection
6.) pregnant or lactating
7.) taking any medications or herbal extracts
8.) vision impairment not corrected

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive Function using Cognitive Drug Research (CDR) battery, Swinburne University Computerised Cognitive aging Battery (SUCCAB) battery[Baseline and 2hours post dose];Cardiovascular function using transcranial doppler ultrasound and arterial stiffness measure (using sphygmocor system)[Baseline and 2hours post dose]

Secondary Outcome Measures

Name	Time	Method
Stress/mood using multitasking battery to induce stress and mood questionnaires before and after stress task[Baseline and 2hours post dose]