Skip to main content
MedPathMedPath Home
Clinical Trials/EUCTR2011-005003-32-NL
EUCTR2011-005003-32-NL
Active, not recruiting
Phase 1

A randomized multicenter clinical trial for patients with multi-organ, colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone.

VU University Medical Center, Department of Medical Oncology0 sites478 target enrollmentMarch 5, 2012
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditionsmulti-organ metastatic colorectal cancerMedDRA version: 21.0Level: LLTClassification code 10052362Term: Metastatic colorectal cancerSystem Organ Class: 100000004864Therapeutic area: Diseases [C] - Cancer [C04]
DrugsXelodaEloxatinAvastinFluorouracilSodiofolin

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
multi-organ metastatic colorectal cancer
Sponsor
VU University Medical Center, Department of Medical Oncology
Enrollment
478
Status
Active, not recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
March 5, 2012
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
VU University Medical Center, Department of Medical Oncology

Eligibility Criteria

Inclusion Criteria

  • •Patients with indication for first line palliative systemic treatment for metatastatic colorectal cancer, with CRC metastases in \= 2 different organs, minimum age 18 years, life expectancy of at least 12 weeks
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range 239
  • •F.1\.3 Elderly (\>\=65 years) yes
  • •F.1\.3\.1 Number of subjects for this age range 239

Exclusion Criteria

  • •Prior (neo\-)adjuvant chemotherapy \< 6 months after last treatment and first detection of metastasis (except for neoadjuvant capecitabin in the context of chemoradiation for rectal carcinoma), candidates for HIPEC, evidence of brain metastases, history of cardiac disease, uncontrolled hypertension, uncontrolled infections, pregnancy or breast feeding

Outcomes

Primary Outcomes

Not specified

Similar Trials

Recruiting
Not Applicable
A randomized multicenter clinical trial for patients with multi-organ colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone.
NL-OMON54652Radboud Universitair Medisch Centrum408
Active, not recruiting
Not Applicable
A randomised multicenter clinical trial for patients with multi-organ, colorectal cancer metastases comparing the combination of chemotherapy and removing as many visible tumors as possible by surgery or other means versus chemotherapy aloneMulti-organ, colorectal cancer metastasesCancer
ISRCTN15067672Radboud University Medical Centre Nijmegen (Netherlands)478
Not yet recruiting
Not Applicable
A randomized controlled multicenter clinical trial of Xinxinfu combined with Qiangxin Fang in the treatment of coronary heart disease complicated with cardiac insufficiency
ITMCTR2000003805Shanghai Municipal Hospital of Traditional Chinese Medicine
Completed
Not Applicable
Multicenter randomized clinical trial in Patients with Juvenile Idiopathic Athritis: Safety and efficacy of vaccination with live attenuated Measles, Mumps, Rubella vaccinejuvenile chronic arthritisjuvenile Idiopathic arthritis1000381610023213
NL-OMON38254niversitair Medisch Centrum Utrecht135
Active, not recruiting
Phase 1
Multicenter randomized clinical trial in Patients with Juvenile Idiopathic Arthritis and Methotrexate related side effects: Psychological Behavioural therapy versus switch to MTX parenteral versus standard of care - MTX tolerance studyPatients with Juvenile Idiopathic Arthritis and Methotrexate related side effects
EUCTR2006-006812-31-DEniversity of Munster120