NL-OMON38254已完成不适用
Multicenter randomized clinical trial in Patients with Juvenile Idiopathic Athritis: Safety and efficacy of vaccination with live attenuated Measles, Mumps, Rubella vaccine - Safety and efficacy of MMR booster vaccination in JIA
niversitair Medisch Centrum Utrecht0 个研究点目标入组 135 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 135
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 2 至 99（—）
入选标准
- •- all subtypes of juvenile idiopathic arthritis
- •- ages 4-9 (this is at least 2,5 years after initial MMR and before the scheduled booster, usually given between age 9-10)
- •- fifteen healthy adults (age 18-65)
排除标准
- •- use of Infliximab (anti-TNF alpha therapy).
- •- primary immunodeficiency
- •- fever less than 48 hour prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •- evidence of viral or bacterial infection less than 48hours prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •- methylprednisolon pulse therapy less than 1 month prior to vaccination (in these cases, the moment of vaccination will be postponed for 1 month)
- •- transfusion of blood or bloodprocudts (e.g.) intravenous immunoglobulines (IVIG) in the 3 months prior to vaccination. (in these cases, the moment of vaccination will be postponed for 3 months);for healthy controls:
- •-serious adverse events to previous MMR vaccination
- •-Use of immunosuppressive drugs
- •-Primary immunodeficiency
- •-Fever less than 48 hour prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •-Evidence of viral or bacterial infection less than 48hours prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •-Methylprednisolon pulse therapy less than 1 month prior to vaccination (in these cases, the moment of vaccination will be postponed for 1 month)
- •-Pregnancy
- •-Lactation
研究者
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