EUCTR2007-001861-14-NL进行中（未招募）不适用
Multicenter randomized clinical trial in Patients with Juvenile Idiopathic Athritis: Safety and efficacy of vaccination with live attenuated Measles, Mumps, Rubella vaccine - safety and efficacy of MMR vaccination in JIA patients
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- all subtypes of Juvenile Idiopathic Arthritis (JIA) patients according to ILAR criteria
- •- ages 4 - 9 (this is 2 years after initial MMR and before the scheduled booster, usually given at age 9)
- •- five healthy controls (18-65 years)
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Use of Infliximab (Remicade, anti-TNF alpha therapy).
- •- Primary immunodeficiency
- •- Fever less than 48 hour prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •- Evidence of viral or bacterial infection less than 48hours prior to vaccination (here the moment of vaccination will be postponed for 1 month)
- •- Methylprednisolon pulse therapy less than 1 month prior to vaccination (in these cases, the moment of vaccination will be postponed for 1 month)
- •for healthy controls:
- •-serious adverse events to previous MMR vaccination
- •-Use of immunosuppressive drugs
- •-Primary immunodeficiency
- •-Fever less than 48 hour prior to vaccination (vaccination will be postponed)
- •-Evidence of viral or bacterial infection less than 48hours prior to vaccination (vaccination will be postponed)
- •-Methylprednisolon pulse therapy less than 1 month prior to vaccination (vaccination will be postponed)
- •-Pregnancy
- •-Lactation
研究者
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