NL-OMON54652
Recruiting
Not Applicable
A randomized multicenter clinical trial for patients with multi-organ colorectal cancer metastases comparing the combination of chemotherapy and maximal tumor debulking versus chemotherapy alone. - ORCHESTRA
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 408
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with indication for first line palliative systemic treatment for
- •metatastatic colorectal cancer, with CRC metastases in \>\= 2 different organs,
- •minimum age 18 years, life expectancy of at least 12 weeks
Exclusion Criteria
- •Prior (neo\-)adjuvant chemotherapy for \< 6 months after last treatment and first
- •detection of extrahepatic metastases, except for neoadjuvant capecitabin in the
- •context of chemoradiation for rectal carcinoma, candidates for HIPEC, patients
- •with livermetastases only, evidence of brain metastases, history of cardiac
- •disease, uncontrolled hypertension, uncontrolled infections, pregnancy or
- •breast feeding
Outcomes
Primary Outcomes
Not specified
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