Intravenous Haloperidol as an adjuvant analgesic for management of cancer pai
Phase 2
- Conditions
- Health Condition 1: - Health Condition 2: C00-D49- Neoplasms
- Registration Number
- CTRI/2023/10/058922
- Lead Sponsor
- Cancer Institute WIA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)All patients who are diagnosed with abdominal cancer and, head and neck cancer, receiving morphine for pain management, in acute severe pain NRS = 7
2)Age 18 – 65 years
Exclusion Criteria
1)People who are already on psychiatric medications or previous psychiatric disorder
2)People in acute delirium or mentally incapacitated or has severe emotional or psychiatric disorder.
3)People with history or current evidence of QT prolongation arrythmia or existing cardiovascular problems
4)People with extrapyramidal symptoms or existing parkinsonism
5)People who are hypotensive, hypothyroid, increased liver function tests
6)People who are allergic to haloperidol
7)People not consenting for the study or inability to give informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the effect of intravenous haloperidol as an adjuvant analgesic in treating acute cancer pain among patients visiting the Palliative care Outpatient Department.Timepoint: numerical rating scale will be assessed for pain at 0 minutes, 15 minutes, 30 minutes, 45 minutes and at the end of 1 hour
- Secondary Outcome Measures
Name Time Method 1.To assess the patient reported onset and duration of response to intravenous haloperidol. <br/ ><br>2.To determine the dose of haloperidol to attain adequate analgesia. <br/ ><br>3.To observe the side effects of administration of intravenous haloperidol <br/ ><br>4.To assess the feasibility of performing the study in the palliative care outpatient department <br/ ><br>Timepoint: within 2 days of intervention