Relationship Between Postoperative Delirium and Heart Function in Valvular Surgery：A Prospective Observational Cohort Study
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- heart function
Study Overview
Brief Summary
Delirium is an acute brain lesion characterized by abnormalities of consciousness, attention, cognition and sensation. Many brain diseases such as stroke, traumatic brain injury and intracranial hypertension can lead to cardiac insufficiency, arrhythmia and heart failure. The incidence of postoperative delirium in patients undergoing cardiac surgery is high. Postoperative delirium is a manifestation of brain function injury. The effect of postoperative delirium on postoperative cardiac function in patients undergoing cardiac surgery is worthy of further discussion.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 60 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing valvular surgery
- •Age between 60 to 75
Exclusion Criteria
- •Have a history of cerebral infarction before operation
- •Cardiac function was seriously impaired before surgery
- •Neuropsychiatric disorders were present before surgery
Outcomes
Primary Outcomes
heart function
Time Frame: up to 60 days
Doses of norepinephrine, epinephrine, dopamine, dobutamine and vasopressin
Secondary Outcomes
No secondary outcomes reported
Investigators
Jun Ma
The chief of department of anesthesiology
Beijing Anzhen Hospital