Detection of parathyroid glands with autofluoresence during thyroid and parathyroid surgery

Not Applicable

Recruiting

• Conditions: Thyroid nodules; Thyroid cancer; Multinodular goitres; Graves' disease; Primary hyperparathyroidism; Renal hyperparathyroidism; Surgery - Surgical techniques; Metabolic and Endocrine - Thyroid disease; Metabolic and Endocrine - Other endocrine disorders; Cancer - Thyroid

• Registration Number: ACTRN12624000151538
• Lead Sponsor: Alfred Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-02-16
• Last Update Posted: 27 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

All adults (greater and equal to 18 years old) patients with thyroid disease who will be undergoing hemi or total thyroidectomy (includes patients who have undergone a prior neck exploration for parathyroid disease or other but have an intact thyroid gland).

All adults (greater and equal to 18 years old) patients with persisting thyroid disease and will be undergoing re-operative or completion thyroidectomy.

All adults (greater and equal to 18 years old) patients with thyroid cancer and will be undergoing re-operative or completion thyroidectomy.

All adults (greater and equal to 18 years old) patients with primary, secondary or tertiary hyperparathyroidism who will be undergoing parathyroid surgery.

All adults (greater and equal to 18 years old) patients with persistent primary hyperparathyroidism after having undergone a failed prior parathyroid surgery who will be undergoing repeat parathyroid surgery.

Exclusion Criteria

Children and minors
Pregnant women
Patients with very high anaesthetic risks

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint of this study is to evaluate the confidence level of surgeons in identifying parathyroid glands during thyroid and parathyroid surgery before and after using the PTeye[ This information is recorded at the time of surgery]

Secondary Outcome Measures

Name	Time	Method
Post-operative hypoparathyroidism rates[ PTH levels will be checked at Day 0,Day 1, 2 weeks and 3 months post surgery];Reduction in the number of frozen sections being used[ This will be recorded intraoperatively];Confidence of surgical trainees in identifying parathyroid glands[ This will be assessed intraoperatively]