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Modulation of motor overflow and surround inhibition during sequential finger movements - an explorative study

Conditions
neurologische aansturing spieren
10028037
Registration Number
NL-OMON42522
Lead Sponsor
niversitair Medisch Centrum Sint Radboud
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
15
Inclusion Criteria

Between 18-30 years old, must be right-handed.

Exclusion Criteria

Presence of wrist pain, previous hand or wrist trauma.
Experience with extensively playing a musical instrument.
Being pregnant.
Ever had brain surgery.
Presence of cardiac pacemaker or intracardiac lines.
Presence of implanted neurostimulator.
Presence of cochlear implants.
Presence of medication infusion device.
History of epilepsy or seizures in participants or close relatives.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>- We expect an effect of time on the motor overflow in intrinsic muscles<br /><br>generated during sequential movements.<br /><br>- The effect of the training and the overflow on surround inhibition will be<br /><br>assessed with single pulse TMS.<br /><br>- Relationship between the amount of motor overflow and the decrease in<br /><br>surround inhibition.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>- We expect that the amount of motor overflow during the sequential movement<br /><br>will be related to the amount of surround inhibition before the start of the<br /><br>training.<br /><br>- We expect to also find motor overflow in the extrinsic muscles. </p><br>
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