Ultrasound Evaluation of Hematoma Risk After Needle EMG in Patient on DOAC Therapy

Recruiting

• Conditions: Direct Acting Anticoagulant Adverse Reaction; Needle Injury; EMG; Peripheral Neuropathies; Mononeuropathies; Polyneuropathies; Neuromuscular Diseases (NMD)

• Registration Number: NCT07166302
• Lead Sponsor: Masaryk University

Brief Summary

Approximately 30 minutes after needle EMG, patients who are taking direct oral anticoagulants (DOACs) will undergo an ultrasound examination to evaluate for the presence of possible intramuscular hematomas at the muscles where the EMG needle was inserted. These hematomas are considered a potential adverse effect of needle EMG.

The aim of the study is to determine whether needle EMG can be considered a safe procedure in this group of patients, without posing a risk of intramuscular hematoma formation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-09
• Study Start: 2025-09-01
• Study First Submitted: 2025-09-03
• Study First Submitted QC: 2025-09-03
• Last Update Submitted: 2025-09-03
• Study First Posted: 2025-09-10
• Last Update Posted: 2025-09-10
• Primary Completion: 2026-06-30
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Subjects must understand the nature of the study and must provide signed and dated written informed consent prior to conducting any study-related procedures
• Willing and able to comply with all protocol procedures
• subjects confirmed the daily (and recent) intake od direct anticoagulants in strandard dosing.
• no other antitrombotic drug therapy (e.g. acetylsalicyl acid, clopidogrel, ticagralol, low molecular weight heparin or second direct anticoagulant) is taken.

Exclusion Criteria

• Any clinically significant medical or psychiatric condition or medical history that, in the opinion of the investigator, would interfere with the subject's ability to participate in the study or increase the risk of participation for that subject
• other antitrombotic drug therapy (e.g. acetylsalicyl acid, clopidogrel, ticagralol, low molecular weight heparin or second direct anticoagulant) is recently taken.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intramuscular hematoma risk	seven days since the needle EMG	Ultrasound evaluation of intramuscular hematoma formation after needle EMG in DOAC patients

Trial Locations

Locations (2)

University Hospital Brno; 🇨🇿 Brno, Czech Republic, Czechia

University hospital Brno; 🇨🇿 Brno, Czech Republic, Czechia