Combined Ketamine and Propofol in electroconvulsive therapy of depressio
Phase 1
- Conditions
- major depressive disorder.recurrent depressive disorder
- Registration Number
- IRCT138811022935N2
- Lead Sponsor
- Kurdistan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
diagnosis by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) (American Psychiatric Association, 2000), of major depressive disorder, age between 18 to 40 years old, Baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 13, IQ>70
Exclusion criteria: drug or alcohol dependence, any contraindication of ECT, depressive disorder with psychotic features, history of epilepsy, ASA class >2, history of cognitive disorder
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: baseline and one day after the third and the last ECT session and 2 weeks after the last session. Method of measurement: Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method