Effect of Intra-articular Injection of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Disc Disorder
- Sponsor
- Ege University
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Change of pain
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + injectable platelet-rich fibrin (i-PRF). As primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.
Detailed Description
This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + i-PRF. Arthrocentesis procedure was performed for all groups with two needle technique. For test group, intra-articular i-PRF was made. As a primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.
Investigators
Gözde Işık
Assistan Professor
Ege University
Eligibility Criteria
Inclusion Criteria
- •unilateral or bilateral disc displacement without reduction
- •localized pain on temporomandibular joint
- •decreased mouth opening, lateral and protrusive movements
Exclusion Criteria
- •Malignant or inflammatory disorders
- •prior surgical history of temporomandibular joint
Outcomes
Primary Outcomes
Change of pain
Time Frame: at preoperatively, and at 1, 2, 3, 6 and 12 months postoperatively
Pain was measured with a 10-point visual analogue scale which range from 0 meaning no pain to 10 meaning worst pain at preoperatively and at 1, 2, 3, 6 and 12 months postoperatively
Secondary Outcomes
- Change of maximum mouth opening(at preoperatively, and at 1, 2, 3, 6 and 12 months postoperatively)
- Change of lateral movements(at preoperatively, and at 1, 2, 3, 6 and 12 months postoperatively)
- Change of protrusive movements(at preoperatively, and at 1, 2, 3, 6 and 12 months postoperatively)