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Evaluation of melatonin's effect on pain and blood loss after cesarean sectio

Not Applicable
Conditions
postoperative hemorrhage.
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
Registration Number
IRCT2012120411665N1
Lead Sponsor
Qazvin University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
120
Inclusion Criteria

pregnant women at term (37—40 wks); cesarean section;spainal anesthesia; with out current or previous history of significant disease including heart disease, liver, renal disorders or known coagulopathy.
Excluding criteria: Anemia (Hb8 g%); multiple gestation; antepartum hemorrhage; poly-hydramnios; two or more previous cesarean sections; a history of previous rupture uterus.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Amount of blood loss after cesarean delivery. Timepoint: determination of Hemoglobin values both before surgery and 12 h following surgery. Method of measurement: determination of Hemoglobin values.;Time to first requirement of analgesic supplement. Timepoint: Time to first requirement of analgesic supplement from the time of injection intrathecal anesthetic solution. Method of measurement: Verbal Pain Scale[ VRS]>4.
Secondary Outcome Measures
NameTimeMethod
Hemodynamic variables. Timepoint: hemodynamic variables 5min before the intrathecal injection,and at 2, 4, 6, 10, 15,20 ,25,30 min after the injection. Method of measurement: measurement by nonivasive automatic blood pressure.;Severity of anxiety. Timepoint: 5min before the intrathecal injection,and at 2, 4, 6, 10, 15,20 ,25,30 min after the injection. Method of measurement: (VAS)Visual Anxiety Scale.
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