Analgesic Efficacy of Pre-emptive Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Patients Undergoing Posterolateral Thoracotomy Incisions: Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- The degree of Postoperative Pain
研究概览
简要总结
This study is designed to investigate the analgesic efficacy of pre-emptive ultrasound-guided midpoint transverse process to pleura (MTP) block for posterolateral thoracotomy in cardiothoracic surgeries.
详细描述
Preemptive preoperative analgesia was first proposed, over the years it has been gradually regarded as an intervention given before incision, facilitating mobilization and functional rehabilitation after surgery, reducing postoperative opioid consumption, decreasing the incidence of adverse events and improving patient satisfaction.
The Mid Transverse Process to Pleura block, described by Costach et al. involves deposition of drug midway between the transverse process and pleura. Costach et al. postulated that the local anesthetic deposited at this point may reach the paravertebral space through several possible mechanisms, such as spread medially through the gap between the superior costotransverse ligament (SCTL) and vertebral bodies, through fenestrations in SCTL, and laterally through the internal intercostal membrane
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 21- and65 years old
- •American Society of Anesthesiologists (ASA) II-III
- •Scheduled for posterolateral thoracotomy operation under general anesthesia
排除标准
- •Patients with bleeding disorders,
- •Mental or cognitive dysfunction
- •History of chronic analgesic or drug abuse
- •Allergy to local anesthetics
- •Local infection at site of block
结局指标
主要结局
The degree of Postoperative Pain
时间窗: 24 hours postoperative
Postoperative pain will be assessed by the Numerical Rating Scale (NRS;0 no pain while 10 is the maximum pain) at 0,4,8,12,18, 24 hours during rest and cough. If the (NRS) is 4 or more, morphine 3mg will be titrated until pain relief is achieved using a short interval between boluses
次要结局
- The amount of Postoperative morphine consumption(24 hours Postoperative)
- Time to the first rescue analgesia request(24 hours Postoperative)
- SpO2/FiO2 ratio(24 hours Postoperative)
研究者
Heba Abdelhamid Mohamed
Resident of Anesthesiology and Surgical Intensive Care and Pain Medicine
Tanta University