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Clinical Trials/NCT03328663
NCT03328663
Completed
N/A

Randomized Trial of a Psychological Intervention to Promote Coping for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation (HCT)

Massachusetts General Hospital1 site in 1 country100 target enrollmentJanuary 1, 2018
ConditionsCancer

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cancer
Sponsor
Massachusetts General Hospital
Enrollment
100
Locations
1
Primary Endpoint
Feasibility of the Intervention (Feasibility Description Below)
Status
Completed
Last Updated
last month

Overview

Brief Summary

This research study is evaluating the impact of a psychological intervention on the quality of life and mood of caregivers of patients undergoing stem cell transplant.

Detailed Description

The purpose of this study is to find out whether a psychological intervention can make the experience of being a caregiver more manageable by improving the participant's quality of life, mood, and caregiving burden during the participant's loved one's transplant process. The psychological intervention will entail six visits with a trained clinician and will take place during the first three months of the participant's loved ones' transplant process. A trained behavioral psychologist or social worker will meet with the participant or talk with the participant over the telephone or video conference for 45 minutes at a time to discuss the participant's caregiver experience and to help the participant develop effective skills to support the participant's loved one as well as participant over the course of the transplant. The study will use a series of questionnaires to measure the participant's quality of life, mood, and overall caregiving burden. Study questionnaires will be completed in the hospital or clinic. The participant will also have the option of completing these questionnaires remotely through a secure web link, over the telephone, or in a mailed paper copy.

Registry
clinicaltrials.gov
Start Date
January 1, 2018
End Date
December 30, 2024
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

El-Jawahri, Areej,M.D.

Principal Investigator

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • Adult caregivers (≥18 years) of patients undergoing autologous or allogeneic HCT at MGH, and they must attend the HCT consent visit with the patient.
  • A relative or a friend who either lives with the patient or has in-person contact with him or her at least twice per week and is identified as the primary caregiver for transplant.
  • Ability to speak English or able to complete questionnaires with minimum assistance of an interpreter.

Exclusion Criteria

  • Significant uncontrolled psychiatric or other co-morbid disease, which the primary oncologist believes prohibits the ability to participate in study procedures

Outcomes

Primary Outcomes

Feasibility of the Intervention (Feasibility Description Below)

Time Frame: 15 months

Feasibility defined if eligible caregivers randomized to intervention attend at least 50% of the intervention visits

Secondary Outcomes

  • Compare Caregiver Quality of Life (QOL) as Measured by the Caregiver Oncology QOL (CarGOQOL) Questionnaire Between the Study Arms(day 60)
  • Compare Caregiving Burden (CRA) Between the Study Arms(day 60)
  • Compare Caregiver Anxiety Using Hospital Anxiety and Depression Scale (HADS) Between the Study Arms(day 60)
  • Compare Caregiver Self-efficacy Using the Cancer Self-Efficacy Scale-Transplant (CASE-t) Between the Study Arms(day 60)
  • Compare Perceived Coping Skills (MOCS) Between the Study Arms(day 60)

Study Sites (1)

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