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Impact of Cooking Process on Meat Protein Digestion and Metabolism

Not Applicable
Conditions
Physiology
Digestive Tract
Heating Process
Registration Number
NCT01685307
Lead Sponsor
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Brief Summary

Few is known on meat protein digestibility in humans and the impact of cooking process, while excessive intake of processed meat has been suggested to increase the risk of colorectal cancer.

This study aims to measure in vivo in humans the real digestibility of beef meat proteins depending 2 cooking processes, using ileal tubes and stable isotopes.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
48
Inclusion Criteria
  • Healthy
  • BMI between 18 an 27
  • Age between 18 and 45 years
Exclusion Criteria
  • Gastrointestinal or liver pathology
  • Diabetes
  • Pregnancy
  • Vegetarian

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
protein digestibilitysingle measure

From ileal recovery of the ingested tracer during 8 h after the meal

Secondary Outcome Measures
NameTimeMethod
nitrogen metabolismsingle measure

Distribution of dietary nitrogen throug metabolic pools

Trial Locations

Locations (1)

Centre de Recherche sur volontaires

🇫🇷

Bobigny, France

Centre de Recherche sur volontaires
🇫🇷Bobigny, France
Gheorghe Airinei
Contact
33 1 48 95 53 34
gheorghe.airinei@avc.aphp.fr
Robert Benamouzig, MD, PhD
Principal Investigator

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