The Impact of the Extrusion Process During Dietary Protein Production on in Vivo Postprandial Amino Acid Availability
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postprandial Plasma Amino Acid Availability
- Sponsor
- University of Exeter
- Enrollment
- 9
- Locations
- 2
- Primary Endpoint
- Plasma amino acid concentrations
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The bulk of research that has investigated the effect of dietary protein on muscle tissue in humans has used isolated, minimally processed protein powders. However, the protein that we consume on a daily basis has typically undergone various processing methods, and evidence suggests these can change the way our bodies metabolise the protein. 'Extrusion' is a common processing method that uses high pressure to produce protein containing cereals and meat replacement foods. There is currently no research looking at how extrusion affects the way a protein source is digested and absorbed in humans. This study will compare the availability of ingested protein in the blood in the hours following consumption of an extruded versus a non-extruded source.
Investigators
Eligibility Criteria
Inclusion Criteria
- •BMI between 18 and
- •Metabolically healthy
Exclusion Criteria
- •Any metabolic impairments
- •cardio/pulmonary diseases.
- •Chronic use of the over the counter medicine
- •A personal or family history of epilepsy, seizures or schizophrenia.
- •Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.
Outcomes
Primary Outcomes
Plasma amino acid concentrations
Time Frame: 5 hours
The rate of appearance of amino acids ingested in the drink
Secondary Outcomes
- Blood glucose(5 hours)
- Resting metabolic rate(5 hours)
- Serum insulin(5 hours)