Comparing the effects of three PROtein-enhancement strategies on exercise-induced Muscle damage in Older adults

Completed

• Conditions: exercise-induced muscle damage; inspanningsgerelateerde spierschade, sarcopenie

• Registration Number: NL-OMON56728
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-07-19
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 199

Inclusion Criteria

- 60 years or older
- Registered for the Nijmegen Four Days Marches (i.e., able to walk 30-50 km on
consequtive days)
- A habitual protein intake <1.2 g/kg/d (based on the PRO55+ screening tool)
- Able to understand and perform the study procedures
- Able to use a smartphone

Exclusion Criteria

- Allergic or sensitive for milk proteins, or lactose or gluten intolerant
- Diagnosed type I or type II diabetes mellitus
- Diagnosed intestinal diseases influencing the uptake of protein (i.e., active
inflammatory bowel disease, Crohn*s disease)
- Consumption of other freely available protein supplements during the study
period.
- If the subject intends to perform additional exercise bouts that cause muscle
damage in the 4 days before the single- and multiple exercise bouts.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Circulating creatine kinase concentration is the primary outcome. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are circulating lactate dehydrogenase<br /><br>concentrations, muscle soreness, and muscle function. </p><br>