Tranexamic acid in reducing bleeding in the femoral shaft fracture surgery
Phase 2
- Conditions
- Fracture of shaft of femur.Fracture of shaft of femur
- Registration Number
- IRCT201111198131N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
femoral shaft fracture; the first time; non-emergency; age 60-18 years; Normotensive being; tourniquet is not used; the amount of Hgb in the range of 12-10; following a period of 3 hours. Exclusion criteria: prohibition hypotension (eg, cardiovascular disease ); previous use of anticoagulants; unexpected factors that complicate or prolong the surgery; to be with multiple trauma; hypertensive patients; reintroduction; diseases that cause clotting disorders; including banning the use of tranexamic acid.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of bleeding. Timepoint: during anesthesia. Method of measurement: Counting blood gases, the suction,and operation field.
- Secondary Outcome Measures
Name Time Method Hypotension. Timepoint: during anesthesia. Method of measurement: by NIBP.;Arhythmia. Timepoint: during anesthesia. Method of measurement: by monitoring of ECG.;Sever bleeding. Timepoint: during anesthesia. Method of measurement: The number of blood gas , Surgery field,suction.