Effect of ammonia-lowering therapy on covert hepatic encephalopathy: a prospective study
Not Applicable
- Conditions
- cirrhosis
- Registration Number
- JPRN-UMIN000044033
- Lead Sponsor
- Gifu University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Not provided
Exclusion Criteria
Presence of overt hepatic encephalopathy or history of OHE in the past 4 weeks; Presence of uncontrolled hepatocellular carcinoma or other malignancies; Previous transjugular intrahepatic portosystemic shunt or shunt surgery; Active ongoing infection; History of gastrointestinal bleeding, infection or spontaneous bacterial peritonitis in the past 4 weeks; Drug or alcohol abuse in the past 4 weeks; Use of benzodiazepines, anti-epileptic or psychotropic drugs; Presence of neurological diseases; Pregnancy; Presence of severe comorbidities such as heart, respiratory, and/or renal failure
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of covert hepatic encephalopathy
- Secondary Outcome Measures
Name Time Method