Spinal anesthesia at low and moderately high altitudes: A comparison of anesthetic parameters and hemodynamic changes

Phase 4

Completed

• Conditions: Spinal anesthesia at low and moderately high altitudes; Anaesthesiology - Other anaesthesiology

• Registration Number: ACTRN12614000749606
• Lead Sponsor: Dr. Mehmet AKSOY

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 140

Inclusion Criteria

Male patients with age between 25-40 years, a body mass index between 20-25 kg/m2, ASA (the classification of the American Society of Anesthesiologists) physical status I or II who were scheduled elective lower extremity surgery with spinal anesthesia were included.

Exclusion Criteria

Smokers, alcohol consumers, patients with psychiatric or neurological disorders, chronic diseases such as diabetes, a body mass index over 25, ASA physical status III or IV and contraindications to spinal anesthesia such as coagulaton disorder and infection at the puncture site were excluded from the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To detect the differences, if any, between moderately highlanders and lowlanders in terms of hemodynamic parameters under neuroxial anesthesia via standard monitorization (Datex-Ohmeda, Helsinki, Finland). [During the operation, patients' mean arterial blood pressure (MABP), heart rate (HR) and oxygen saturation were recorded every 5 minutes using a standard monitorization (Datex-Ohmeda, Helsinki, Finland). ]

Secondary Outcome Measures

Name	Time	Method
duration of the block procedure [the time from the start of the anesthetic procedure to the development of full motor block. Complete motor block was defined as a Bromage score of 3. ];duration of surgery [the time from the start of the surgical incision to the completion of surgery];Highest sensory block level was assessed using Modified Bromage scale. [during surgery (the values in 5,10,20,30,90 th minutes). ];sensory block time [from local anesthetic injection to the recovery of S2 dermatom];motor block duration [the time from local anaesthetic injection to complete motor function recovery.Complete motor block was defined as a Bromage score of 3. ];anaesthetic complications such as PDPH (increased pain intensity upon standing up from a supine position). [during surgery and postoperative period for up to 24 hours.]