Effects of Acetazolamide on intracranial pressure in glaucoma

Completed

• Conditions: 10018307; Glaucoma; POAG

• Registration Number: NL-OMON48559
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 35

Inclusion Criteria

*50-70 years of age
*Presence of DPOAEs in at least one ear
*Written informed consent.
*For patients only: taking acetazolamide as part of their regular IOP-lowering medication

Exclusion Criteria

*No presence of DPOAEs
*Any other medications that may influence ICP
*For healthy controls, glaucoma or family history of glaucoma. This will be determined by form F1a and the ophthalmologic screening described in section 3.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Peak and trough values of ICP (phase shifts of DPOAEs) and IOP for patients and<br /><br>controls, for patients measured before and after taking their acetazolamide.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>