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Clinical Trials/NCT00443586
NCT00443586
Unknown
Not Applicable

Age-27 Follow-up of Early Preventive Intervention

University of Colorado, Denver1 site in 1 country345 target enrollmentSeptember 2004

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Risk Reduction Behavior
Sponsor
University of Colorado, Denver
Enrollment
345
Locations
1
Primary Endpoint
Economic productivity (e.g., unemployment, employment in jobs with limited opportunities for career growth, use of welfare, rates of out-of-wedlock births)
Last Updated
4 years ago

Overview

Brief Summary

This study will evaluate the long-term effects of a prenatal and early childhood home nurse visitation program for socially disadvantaged women and their children.

Detailed Description

Nearly half a million children are born each year to single, low-income mothers. Children born to socially disadvantaged mothers are more likely to experience chronic health problems, encounter child abuse and neglect, and receive insufficient health care. Home visitation by nurses during pregnancy and early childhood may prevent a wide range of health and developmental problems in children born to women who are either teenagers, unmarried, or of low economic status. This study is associated with a home nurse visitation program that first began with 400 socially disadvantaged pregnant women between the years of 1977 and 1980 in an upstate New York semi-rural county. Participants in the original study were randomly assigned to participate in the home nurse visitation program or receive comparison services from pregnancy until the child's second birthday. Participants assigned to receive comparison services were provided with free transportation for prenatal and child care, as well as sensory and developmental screening for the child. Participants assigned to the home nurse visitation program were visited at home by a nurse 9 times during pregnancy and 23 times during the child's first 2 years of life. A follow-up study concluded that the home nurse visitation program reduced the number subsequent pregnancies, use of welfare, child abuse and neglect, and criminal behavior on the part of the socially disadvantaged mothers for up to 15 years after the birth of their first child. This follow-up study will determine whether a home nurse visitation program has continued long-term effects on a child's health and development, 27 years later. Specifically, this study will evaluate whether the nurse-visited young adult offspring differ from the comparison group in their economic productivity; rates of child abuse and neglect; criminal behavior; mental health; abuse of substances; use of welfare, foster care, and healthcare in relation to government expenditures; and quality of their partnered relationships. Participants within the nurse-visited program group will be compared with each other to determine whether certain characteristics or factors, such as genetic vulnerabilities, environmental risks, or a history of child abuse, make someone less likely to benefit from a home nurse visitation program.

Registry
clinicaltrials.gov
Start Date
September 2004
End Date
December 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Offspring of mothers who had participated in Elmira, N.Y. randomized clinical trial of prenatal and infant/toddler home visiting by nurses.
  • Participants needed to be at least 27 years of age.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Economic productivity (e.g., unemployment, employment in jobs with limited opportunities for career growth, use of welfare, rates of out-of-wedlock births)

Time Frame: Measured when child turns 27 years old

Quality of partnered relationships (violence, commitment, and communication)

Time Frame: Measured when child turns 27 years old

Rates of child abuse and neglect

Time Frame: Measured when child turns 27 years old

Rates of criminal behavior, arrests, convictions, and imprisonment

Time Frame: Measured when child turns 27 years old

Government expenditures and higher tax revenues

Time Frame: Measured when child turns 27 years old

Mental health and abuse of substances

Time Frame: Measured when child turns 27 years old

Study Sites (1)

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