Low Fructose Diet in Diabetes Type 2

Not Applicable

• Conditions: Fructose Metabolism Disorder
• Interventions: Other: low frutose diet

• Registration Number: NCT03352596
• Lead Sponsor: National Nutrition and Food Technology Institute

Brief Summary

Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Status Verified: 2017-08
• Primary Completion: 2017-10-01
• Study First Submitted: 2017-11-13
• Study First Submitted QC: 2017-11-20
• Last Update Submitted: 2017-11-20
• Study First Posted: 2017-11-24
• Last Update Posted: 2017-11-24
• Study Completion: 2017-11-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

1. Age of 70-40 years
2. body mass index(BMI) between 18.5 and 27
3. Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)

Exclusion Criteria

1. Pregnancy and lactation
2. Thyroid gland disorders
3. Kidney disease and inflammation
4. Follow the weight loss regimen 6 months before starting the study
5. Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3
6. Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
intervention group	low frutose diet	Eight weeks of low fructose diet with a maximum of 12 g of fructose

Primary Outcome Measures

Name	Time	Method
Homeostatic model assessment and insulin resistance(HOMA-IR)	8weeks
insulin	8 weeks
fasting blood suger(FBS)	8 weeks

Secondary Outcome Measures

Name	Time	Method
LDL-C	8 weeks
Total cholestrole	8 weeks
HDL-C	8 weeks
Triglyceride	8 weeks
Blood pressure	8 weeks