Hepatectomy for Early-stage HCC Patients With CSPH

Completed

• Conditions: Portal Hypertension; HCC
• Interventions: Procedure: hepatectomy

• Registration Number: NCT05402644
• Lead Sponsor: Tongji Hospital

Brief Summary

Clinically significant portal hypertension (CSPH) can affect the surgical prognosis of early-stage (BCLC stage A) HCC. An additional stage, such as the BCLC stage A-B, can be considered.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-12-01
• Primary Completion: 2017-01-01
• Status Verified: 2021-05
• Study Completion: 2022-01-01
• Study First Submitted: 2022-05-26
• Study First Submitted QC: 2022-05-30
• Last Update Submitted: 2022-05-30
• Study First Posted: 2022-06-02
• Last Update Posted: 2022-06-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

HCC was diagnosed by two experienced pathologists in Child-Pugh grade A/B negative resection margin Initial diagnosis of HCC in the patients

Exclusion Criteria

Distant transfer Not HCC

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CSPH	hepatectomy	BCLC stage A patients who underwent hepatectomy in the group with clinically significant portal hypertension (CSPH)
Non-CSPH	hepatectomy	BCLC stage A patients who underwent hepatectomy in the group without clinically significant portal hypertension (Non-CSPH)

Primary Outcome Measures

Name	Time	Method
death	2009--2025	Patient survival time after surgery
recurrence	2009--2025	Patient recurrence time after surgery