The use of HPI (Hypotension probability indicator) during major intracranial surgery, prospective single-center randomized study.

Not Applicable

Completed

• Conditions: hypotension; Anaesthesiology - Other anaesthesiology; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12621000162819
• Lead Sponsor: niversity Hospital Pilsen, Czech Republic

Brief Summary

According to primary outcome, using HPI parameter in anaesthesia in cranial surgery does not lower peri-operative hypotension in statistically significant manner.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-06-30
• Study Start: 2021-02-16
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Major supratentorial brain surgery for tumor resection.
Expected length more than 1hour.
ASA physical status 1-3

Exclusion Criteria

ASA physical status 4-5.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of hypotension through surgery.<br>The incidence of hypotension was retrospectively calculated from blood pressure medical record, which was continually gained (each 20 seconds) during the surgery.[The value of blood pressure was assessed in 20 second intervals throughout the whole surgery.];Incidence of hypotension in maintenance phase of anaesthesia.<br>Incidence was assessed from digital medical record of blood pressure values throughout the anaesthesia, hypotension was defined as mean arterial pressure (MAP) below 65mmHg.[The value of blood pressure was assessed in 20 second intervals throughout the maintenance phase of anaesthesia. Maintenance phase of anaesthesia was defined as period starting 30minutes after induction of anaesthesia. ]

Secondary Outcome Measures

Name	Time	Method
Morbidity in 30 days after surgery.<br>Outcome was assessed from hospital Medical Records System.[30 days after surgery];Full blood analysis (haematocrit, lactate, sodium, pH) was performed by Werfen GEM Premier 3500 device (Werfen Czech, Prague, Czech Republic) immediately after surgery and 6hours after - composite outcome.[Immediately after surgery and 6 hours after.];Amount of infused fluids through surgery.<br>Outcome was assessed from medical records system.[Outcome was assessed at the end of procedure.];Mortality.<br>Outcome was assessed from hospital Medical Records System.[Mortality within one year of the follow-up. (One year after surgery)]