A comparison between Ivabradine (oral) and Labetalol(oral) for decreasing response to laryngoscope and intubation in laparoscopic abdominal surgery
Phase 4
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2023/06/054194
- Lead Sponsor
- Muthu Vignesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of ASA status 1 and 2
2. Patients with airway of Mallampati grade 1 and 2
3. Patients undergo elective laparoscopic abdominal surgery under general anaesthesia
Exclusion Criteria
1. Patients refusal for study
2. Patients of ASA physical status 3 and 4
3. Allergy to drugs under study
4. Patients with significant bradycardia, hypotension and conduction blocks
5. Patients with cardiac, hepatic and renal disorders
6. Patients with anticipated difficult intubation (Mallampati grade 3 and 4) and requiring two attempts and more than 15 seconds at intubation
7. Patients receiving treatment with either of the drug under study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess & compare the changes in hemodynamic parameters of oral ivabradine & oral labetalol during laryngoscopy & endotracheal intubation.Timepoint: 2 hours before induction of anaesthesia to 4 hours after induction or desufflation whichever comes later. <br/ ><br>
- Secondary Outcome Measures
Name Time Method To assess the side effects in the form of hypotension, bradycardia & any possible side effects if anyTimepoint: 2 hours before induction of anaesthesia to 4 hours after induction or desufflation whichever comes later.