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Comparing the effect of oral ivabradine versus oral propranolol premedication during controlled hypotensive anesthesia in functional endoscopic sinus surgery

Not Applicable
Recruiting
Conditions
Anaesthesia
Registration Number
PACTR202111574906850
Lead Sponsor
Ain shams university
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

oASA physical status I and II.
oAge group: 18-40 years old.

Exclusion Criteria

oPatients with cardiovascular disease (hypertension , congestive heart failure , coronary artery disease , AF).
oPatients on beta-blockers.
oPatients with baseline heart rate < 60 beats per minute.
oPatients with diabetes mellitus (DM).
oCerebrovascular insufficiency.
oCoagulation defects.
oHistory of renal or hepatic insufficiency.
oHypersensitivity to the study drugs.
oPatients with history of bronchial asthema.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hemodynamic variables: <br>oMean arterial blood pressure (MABP) in mmHg by non- invasive monitoring . <br>oHeart rate: (beats / minute) . <br>;Amount of Blood loss <br>Intraoperative bleedi
Secondary Outcome Measures
NameTimeMethod
The amount of nitroglycerin used;Incidence of Complications
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