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临床试验/NCT06480682
NCT06480682尚未招募不适用

Prevalence of Relative Energy Deficiency in Sport and Dance

University of Wolverhampton1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年9月10日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
200
试验地点
1
主要终点
Relative energy deficiency (REDs)

研究概览

简要总结

The International Olympic Committee recently published its consensus statement on relative energy deficiency syndrome (REDs) in sport which was followed by a similar version for dance by clinicians and researchers in dance. REDs is a complex multisystem syndrome with low energy availability as its foundation. Dancers and gymnasts, particularly in ballet, have long been reported to have body weight issues with an increase prevalence of eating disorders which has been associated with early onset osteoporosis. Combat sports have a similar issue, with athletes needing to "make weight" to compete in their ideal weight category that has lead to similar eating disorder and associated issues to dance. Currently there are no data on REDs prevalence in dance, gymnastics or combat sports and therefore understanding the underlying prevalence of REDs in both these populations will provide important information for both clinicians and coaches to help develop a safe and healthy environment for their dancers and athletes to compete/perform and to be able to retire from sport/dance without an increased risk of osteoporosis. In a few sports and dance genres, some participants might be more prone to a negative health effect referred to as relative energy deficiency syndrome (REDs). This is an energy deficiency relative to the balance between dietary energy intake and energy availability required to support homeostasis, health and activities of daily living, growth and sporting activities that can result in multiple systems being affected including decreases in bone health, energy metabolism, reproductive function, musculoskeletal health, immunity, glycogen synthesis and cardiovascular and haematological health. The purpose of this study is to examine the prevalence of REDs in specific sports (combat sports and gymnastics) and dance genres (ballet and musical theatre). Voluntary participants will be tested three times a year over a 5-year period. This will include an annual dual-energy x-ray absorptiometry and blood tests plus resting energy expenditure and questionnaires three times a year.

详细描述

Participants will be asked to be available three times for testing over a 12-month period, for a period of 3-years. Their initial test visit will be at a university exercise science laboratory whilst the other testing sessions will occur at their place of work/training.

Each year the initial testing session will include a bone health scan (DXA), a blood sample (2x 5ml samples), a body composition analysis (bioimpedance), resting metabolic rate test and a series of questionnaires. Subsequent test session will include the same tests except the DXA scan unless there is a medical reason to carry out a further scan (two or more bone stress injuries).

The DXA scan, where participants will need to lie still for approximately 20 minutes will monitor body composition, bone mineral density and bone mineral content for the whole body and at the forearm (radius), lower spine (Lumbar 4 and 5) and upper leg (femur). The scan will also look at the ratio between outer (cortical) and inner (trabecular) bone content.

The blood samples will measure a series of markers that have been associated with low energy availability for male and female participants and amenorrhea for female participants.

Anthropometric measurements will consist of body composition analysis will consist of a body composition, stature and body mass. The participant will have their height measured and then stand on bioimpedance scales and hold onto two handles. This will allow changes in body composition changes to be monitored throughout the year without exposing the participant to further radiation from the DXA.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
16 Years 至 45 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Full-time training at either a NGB centre, dance company, vocational dance school or academy
  • Engaged in full-time training at start of project
  • Exclusion Criteria
  • Not engaged in full-time training
  • Injury preventing engagement in training

排除标准

  • 未提供

结局指标

主要结局

Relative energy deficiency (REDs)

时间窗: Throughout study; an average of 3 times a year

Prevalence of REDs in cohorts by diagnosis by elimination by medical team.

次要结局

  • Bone stress injuries(Number of participants with bone stress injuries. Throughout study an average of 3 times a year)
  • Primary Amenorrhea (females)(Number of participants with primary and secondary amenorrhea. Throughout study an average of 3 times a year)
  • Resting Metabolic rate(Throughout study; an average of 3 times a year)
  • Monitoring of all blood markers for below normal values (red flags)(Throughout study; an average of 3 times a year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Matthew Wyon

Professor in Exercise Physiology

University of Wolverhampton

研究点 (1)

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