Vascular Inflammation Stratified by Body Size Phenotype

Korea University1 site in 1 country250 target enrollmentMarch 2008

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Atherosclerosis
Sponsor: Korea University
Enrollment: 250
Locations: 1
Primary Endpoint: max TBR values stratified by the four body size phenotypes
Status: Completed
Last Updated: 12 years ago

Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque
Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention
Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes

Registry

clinicaltrials.gov

Start Date

March 2008

End Date

March 2011

Last Updated

12 years ago

Study Type

Observational

Sex

All

Sponsor

Responsible Party

Principal Investigator

K. M. Choi

Professor

Korea University

•history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
•stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
•history of inflammatory conditions that affect the study results
•taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months
•or malignancy or severe renal or hepatic disease