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临床试验/NCT01979068
NCT01979068已完成不适用

Vascular Inflammation Stratified by Body Size Phenotype

Korea University1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2008年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
250
试验地点
1
主要终点
max TBR values stratified by the four body size phenotypes

研究概览

简要总结

  • Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque
  • Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention
  • Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy patients for visiting routine medical check in our clinic

排除标准

  • history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
  • stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
  • history of inflammatory conditions that affect the study results
  • taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months
  • or malignancy or severe renal or hepatic disease

结局指标

主要结局

max TBR values stratified by the four body size phenotypes

时间窗: 12 weeks

次要结局

  • Framingham risk scores according to the four body size phenotypes(12 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

K. M. Choi

Professor

Korea University

研究点 (1)

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