RBR-9msccy
Active, not recruiting
未知
Clinical and electrophysiological analysis of forel's field h1 deep brain stimulation on motor symptoms, cognitive variables and quality of life
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Parkinson's disease
- Sponsor
- Hospital Santa Marcelina
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients diagnosed with Idiopathic Parkinson's disease according to the criteria of Queen Square Brain Bank; be over 35 years of age and less than 80 y\-old; staging of Parkinson's Disease (Hoehn and Yahr scale), greater than 2 when evaluated in the absence of antiparkinsonian drugs effect; preserved clinical response to levodopa, the patient should present at least 30 percent reduction in the score of motor score the UPDRS scale; significant motor dysfunctions for 3 hours per day or more, despite the best drug treatment; persistent motor dysfunction for at least 1 month despite drug adjustment; patient's desire to receive deep brain stimulation as a therapeutic option in PD; adequate cognitive performance for the demand associated with the necessary care in the postoperative, with the DBS equipments, and in the recognition of adverse events; availability of the caregiver or family member, and of the patient himself, to come in frequent returns to ensure the best parameters of brain stimulation
Exclusion Criteria
- •Parkinsonism associated with other neurodegenerative diseases (multisystemic atrophy; dementia with Lewy bodies; corticobasal degeneration; frontotemporal dementia; spinocerebellar ataxia); vascular parkinsonism; parkinsonism associated with antidopaminergic drugs; normal pressure hydrocephalus; traumatic brain injury; previous surgical treatment for Parkinson's Disease (pallidotomy, thalamotomy, campotomy or deep brain stimulation); patients with uncompensated systemic pathology; Parkinson's disease associated psychosis; major depression according to DSM\-IV criteria \- American Psychiatric Association 2000; dementia associated with Parkinson's disease, according to the criteria of the Movement Disorders Society
Outcomes
Primary Outcomes
Not specified
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