Ex vivo clot lysis measurements in blood samples of healthy volunteers.

Completed

• Conditions: Hyperfibrinolyse; increased bloodclot breakdown; 10064477

• Registration Number: NL-OMON36990
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Healthy volunteers aged 18-40 years.

Exclusion Criteria

anticoagulant or antiplatelet medication, pregnancy, history of hematologic disorders, history of deep venous thrombosis of pulmonary embolism

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter/endpoint is the Lysis onset time (time to the start of<br /><br>hyperfibrinolysis) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters/endpoints are: Blood coagulation (INTEM, EXTEM,<br /><br>APTEM and FIBTEM) and fibrinolytic parameters (Maximum lysis (ML), Lysis Index<br /><br>at 30 and 45 minutes after clot formation (LI30, LI45) and lysis time (LT) and<br /><br>platelet aggregation index</p><br>