Evaluation of Respiratory Parameters and Functional Capacity in Coronary Artery Patients

Active, not recruiting

• Conditions: Coronary Artery Disease

• Registration Number: NCT05549739
• Lead Sponsor: Hacettepe University

Brief Summary

The purpose of this study is to evaluate respiratory parameters and functional capacity in coronary artery patients.

Detailed Description

Decreased pulmonary function as measured by forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), or peak expiratory flow (PEF) has been associated with an increased risk of cardiovascular mortality and morbidity. A low MIP value may generally indicate weak muscle strength and therefore be an indicator of general poor health. Respiratory muscle weakness and decreased respiratory muscle endurance affect exercise tolerance in individuals with chronic disease, including cardiovascular disease. Studies have supported the association of grip strength with frailty, physical activity, diabetes, functional limitation, nutritional status, metabolic syndrome, and mortality.

The study will evaluate respiratory parameters and functional capacity in coronary artery patients.

Study Timeline

• Study First Submitted: 2022-09-18
• Study First Submitted QC: 2022-09-21
• Study First Posted: 2022-09-22
• Study Start: 2022-09-23
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-20
• Last Update Posted: 2022-10-21
• Primary Completion: 2022-11
• Study Completion: 2022-11

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients with coronary artery disease
• Volunteering to participate in the research

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Exclusion Criteria

• Having a musculoskeletal problem
• Having unstable cardiac disease
• Having chronic heart failure (NYHA III-IV)
• A history of acute coronary syndrome or surgical revascularization less than 3 months ago
• Having arrhythmia
• Having the last stage of kidney disease
• Having active myocarditis or pericarditis

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory muscle strength	Day 1	Respiratory muscle strength will be evaluated using a mouth pressure device.
Respiratory muscle endurance	Day 1	Respiratory muscle endurance will be evaluated using a constant load test.
Six-minute-step test	Day 1	The number of steps the participant climbed up and down is recorded.

Secondary Outcome Measures

Name	Time	Method
Functional Capasity	Day 1	The functional capacity is assessed with The Duke Activity Status Index (DASI).
Pulmonary functions	Day 1	Forced vital capacity (FVC), Forced expiratory volume at one second (FEV1), Peak expiratory flow (PEF) assessment via spirometry.
Hand grip strength	Day 1	Hand grip strength is evaluated by a hand dynamometer.

Trial Locations

Locations (1)

Hacettepe University; 🇹🇷 Ankara, Turkey