Probiotics and Infections in Children Attending Day Care Centres
Phase 3
Completed
- Conditions
- Respiratory Tract InfectionsGastrointestinal Diseases
- Interventions
- Dietary Supplement: ProbioticOther: Placebo
- Registration Number
- NCT01014676
- Lead Sponsor
- Valio Ltd
- Brief Summary
The purpose of this study is to evaluate the effect of regular consumption of probiotic milk in preventing illnesses in Finnish children attending day care centres, and possible cost-benefits that could be associated with fewer illnesses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age 2 to 6 years in the beginning of the intervention
- Attendance at a day care centre participating in the study (5 days a week)
Exclusion Criteria
- Milk allergy or lactose intolerance
- Congenital heart diseases that requires regular medication
- Malign diseases
- Cytostatic treatment
- Use of biological rheumatic medication
- Continuous microbial medication
- Regular use of oral corticosteroids (inhalable accepted)
- Diabetes
- Simultaneous participation in other clinical trials
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Probiotic milk Probiotic - Standard milk Placebo -
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie probiotic efficacy in reducing respiratory and gastrointestinal infections in NCT01014676?
How does Valio Ltd's probiotic milk compare to standard-of-care interventions for daycare-associated infections in children?
Which gut microbiota biomarkers correlate with response to probiotic supplementation in NCT01014676 pediatric trials?
What adverse events are reported with long-term probiotic milk consumption in NCT01014676 and how are they managed?
Are there synergistic effects combining Lactobacillus rhamnosus GG with prebiotics for infection prevention in daycare children?
Trial Locations
- Locations (1)
Clinical Life Sciences Inc.
🇫🇮Kajaani and Oulu, Province of Oulu, Finland