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Clinical Trials/NCT01254812
NCT01254812
Completed
Not Applicable

Changes on Pulmonary Function After Application of a Bilateral-dual TAP-block

Bispebjerg Hospital1 site in 1 country12 target enrollmentOctober 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Operative Pain
Sponsor
Bispebjerg Hospital
Enrollment
12
Locations
1
Primary Endpoint
Forced expiratory volume in 1 second (FEV1)
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

TAP-block (Transverse Abdominal Plane) block is a method of regional anesthesia used after abdominal surgery. The method is often applied ultra-sound guided.

In our department, the so-called bilateral dual TAP-block (BD-TAP-block) has been developed. This includes injection of local anesthetics at four sites on the abdominal wall, aiming at the best possible spread of the nerve block.

Clinical experience shows satisfying results on pain relieve using the nerve block, i.e the sensory nerves of the abdominal wall are successfully blocked. However, to our knowledge, clinical investigations regarding the effect on the muscles of the abdominal wall has never been executed.

Patients with chronic lung diseases, who are prone to catch pneumonia post surgery, may have to be able to use accessory muscle groups to prevent pulmonary phlegm stagnation. Therefore it would be inappropriate if the motor nerves supplying these muscles were too, affected by the nerve block.

Our clinical experience has so far not given us suspicion or indication that the motor nerves become blocked, although these nerves are situated in the same muscle layer as the sensory branches.

Hence the investigators would like to examine on healthy, male subjects, whether application of a bilateral-dual TAP-block effects their ability to perform peak-flow and inspiratory and expiratory pressure. Our study hypothesis is:

There is no clinically relevant difference in the spread of results of pulmonary tests (peak flow et.c.) before and after application of bilateral dual TAP-block.

Registry
clinicaltrials.gov
Start Date
October 2010
End Date
December 2010
Last Updated
14 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Christian Maschmann

MD

Bispebjerg Hospital

Eligibility Criteria

Inclusion Criteria

  • No history of asthma
  • Young male
  • Has to be able to conduct lung function examination and the application of abdominal nerve block

Exclusion Criteria

  • History of asthma

Outcomes

Primary Outcomes

Forced expiratory volume in 1 second (FEV1)

Time Frame: 1 hour after application of the BD-TAP-block

Secondary Outcomes

  • Expiratory/Inspiratory pressure(1 hour after application of the BD-TAP-block)

Study Sites (1)

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