Changes in Brain Tissue Pulsatility With Musical Stimuli

Completed

• Conditions: Healthy

• Registration Number: NCT03867422
• Lead Sponsor: University Hospital, Tours

Brief Summary

Music Perception is well known to elicit emotions and neuronal activations. Changes in the cerebrovascular physiology have also been found in emotional tasks but only few studies have investigated markers of cerebrovascular physiology in a music task and no study has used the Ultrasound method of Tissue Pulsatility Imaging (TPI) in a music task. The use of TPI to measure reactivity of Brain Tissue Pulsatility Imaging (BTP) could further elucidate the cerebral basis of music perception.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-03-04
• Study First Submitted QC: 2019-03-05
• Study First Posted: 2019-03-08
• Study Start: 2019-04-02
• Primary Completion: 2019-04-26
• Study Completion: 2019-04-26
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-20
• Last Update Posted: 2019-08-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• more or equal 18 years-old and less or equal 45 years-old
• no known hearing problem

Exclusion Criteria

• professional musician
• history of neurologic, psychiatric or cadiologic disease
• treatment which could impact parameters of brain tissue pulsatility and peripheral nervous system
• opposition to use the data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
amplitude of variations in brain tissue pulsatility	Baseline	in micrometers

Secondary Outcome Measures

Name	Time	Method
skin conductance	Baseline	in milliVolt
heart rate	Baseline	beat by minute
score of barcelona music reward questionnary (BMQR)	Baseline	BMQR: Barcellona Music Reward Questionnaire for the evaluation of musical anhedonia; * Only the total score of musical reward will be reported; for total score, minimum value is 20, maximum value is 100. Values under 40 represent low values in the overall score; values above 60 indicate high values in the overall score; * High global score (\>60) represents a better outcome; low global score (\<40) represents a worse outcome, notably an impairment in music reward processing; * The overall score is computed by adding raw scores of the items (except for items 2 and 5, which need to be reversed).
breathing rate	Baseline	Frequency

Trial Locations

Locations (1)

DESMIDT; 🇫🇷 Tours, France